Comprehensive view of the stem cell biology; potential uses of stem cell in clinical practices; stem cell biology of both embryonic and adult stem cells including characteristics at cellular and molecular levels; signaling transduction; stem cell interactions with their microenvironment and their role in tissue homeostasis; basic technology involved in stem cell research; hematopoietic stem cell transplantation as a standard treatment for hematological disorders; potential uses and limitations of stem cells for the treatment of diseases other than hematological disorders; ethics in animal care and use for research; ethical issues of stem cell applications